Drink a Pre-Alcohol
For best results, make Pre-Alcohol your first drink of the night.
Drink responsibly
Whether it’s a glass of wine with dinner or going out with friends, pace yourself, hydrate, and get a good night’s sleep.
Enjoy tomorrow
Seize your next day—hit the gym, get outside, play with the kids—make the most of it.
What is ZBioticsR Pre-Alcohol Probiotic Drink?
Pre-Alcohol is a beverage containing a patented, genetically engineered probiotic (B. subtilis ZB183™) that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted alcohol byproduct called acetaldehyde – the main culprit behind rough mornings after drinking.
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Alcohol produces acetaldehyde
When we drink, our bodies break down alcohol into an unwanted byproduct called acetaldehyde.
That byproduct is largely responsible for how we feel the day after drinking.
Acetaldehyde builds up in the gut
Acetaldehyde forms in two places: the liver and the gut.
The liver produces an enzyme that removes it quickly. But the gut does not. So acetaldehyde builds up and lingers, filtering out into the rest of our body over time.
Pre-Alcohol breaks it down
Pre-Alcohol helps our gut catch up by temporarily adding a probiotic that can break down acetaldehyde.
This probiotic – Bacillus subtilis ZB183™ – has been engineered to produce the same type of enzyme as our liver: one that digests acetaldehyde.
Proudly built with genetic engineering
The ZBiotics team invented the probiotic in Pre-Alcohol – Bacillus subtilis ZB183™ – using genetic engineering.
Our approach to biotechnology is safety-first and grounded in the strictest ethical principles. We build responsibly or we don’t build at all.
How To Use
The Science
The world’s first genetically engineered probiotics: purpose-built to improve daily life.
Learn about Pre-Alcohol
We start with a natural probiotic bacteria you already eat every day, called Bacillussubtilis. We then used a process naturally honed by bacteria to insert theinstructions for making ALDH into the bacteria's genome...
Learn about Sugar-to-Fiber
Fiber plays an important role in our health but most of us aren't getting enoughfiber in our modern diets. We need 25-30 grams of fiber per day but about 95%of us don't meet that goal...
Built on evidence
You probably have some questions
Check out our FAQs to find answers to common questions and feel free to reach out if you have more.
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How does Pre-Alcohol work?
How does Pre-Alcohol work?
Pre-Alcohol is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver produces. That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that accumulates in your gut when you drink.
Your liver does not have access to your gut. But by drinking Pre-Alcohol, the goal is to augment your gut’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that Pre-Alcohol does not affect intoxication or make alcohol safer to drink, so always drink responsibly.
When do I drink Pre-Alcohol?
When do I drink Pre-Alcohol?
When you're drinking. The earlier the better.
The probiotic in Pre-Alcohol needs time to “wake up” in your gut, so we say the earlier the better if you can remember it. We drink Pre-Alcohol just before going out – right before our first drink. But it should be active if you drink it any time during the day or evening. So whether it’s a few hours before drinking, right with your first drink, or even if you’ve already enjoyed a round or two, go for it.
How long does 1 bottle of Pre-Alcohol last after I drink it?
How long does 1 bottle of Pre-Alcohol last after I drink it?
The probiotic in Pre-Alcohol is likely to stay in your body for 18-24 hours after you drink it. So one bottle will cover you for a whole day, even if you're starting with brunch mimosas followed by evening plans later on!
Does Pre-Alcohol expire?
Does Pre-Alcohol expire?
Pre-Alcohol expires 18 months after bottling. Check the “BB” (Best-By) date on your bottle or box.
Store Pre-Alcohol at room temperature with the cap on. Do not refrigerate. Do not open it until you’re ready to drink it; opening it could potentially let contaminants from the air into the bottle.
Is Pre-Alcohol FDA-compliant?
Is Pre-Alcohol FDA-compliant?
Yes. Pre-Alcohol is fully FDA-compliant for safety and adheres to all regulatory requirements for sale in the U.S.
Note that FDA compliance is not FDA approval. FDA approval is a process reserved for drug products. Pre-Alcohol is a food/beverage product and has not been approved as efficacious for any purpose by the FDA.
Does Pre-Alcohol affect my level of intoxication?
Does Pre-Alcohol affect my level of intoxication?
No.
Pre-Alcohol will not affect your level of intoxication. Pre-Alcohol does not decrease your blood alcohol level, nor does it make alcohol any safer.
All the same rules about alcohol safety apply. Don’t get behind the wheel, don't operate heavy machinery, and don't drink too much. Alcohol is still dangerous on its own
Will Pre-Alcohol change my microbiome?
Will Pre-Alcohol change my microbiome?
That's not how it's designed.
We intentionally designed Pre-Alcohol so that it would not change your microbiome. We purposefully built our probiotic using a base bacteria that is well-adapted to passing straight through you and not colonizing your gut.
This creates a few likely benefits: (1) your microbiome remains unchanged; (2) the interaction between our probiotic and your gut should remain consistent and predictable; and (3) because we’re not trying to change your microbiome, we don’t need to use an excessive amount of probiotic per serving.